Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.8
USERS' SCORE
Moderately Good
Based on 27 Reviews
7.5
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin K2(as Menaquinone-7) (MK-7 ) (MenaQ7®)
100 mcg
**
Top Medical Research Studies
9
We examined how Menaquinone-4, a form of vitamin K2, could help protect the heart during a critical event known as ischemia-reperfusion (I/R) injury, which often occurs after heart attacks. In our study, we used thirty-two rats, dividing them into three groups: a control group that experienced I/R without treatment, a group that received MK-4 before the injury, and another group that got MK-4 at the beginning of the recovery phase.
By using a specialized apparatus to assess heart function, we measured various indicators of heart health, including the pressure the heart could generate and rates of heart contractions. We also examined markers of heart damage and stress, like enzymes and inflammatory signals.
Our findings were promising. The group that received MK-4 after the I/R injury showed a significant reduction in the size of heart damage, alongside improved heart function. This group also had lower levels of markers related to heart stress and damage, indicating that MK-4 might help the heart recover from the stress of a heart attack. Overall, these results suggest that vitamin K2 could be a valuable ally in enhancing heart health during recovery from ischemic events.
By using a specialized apparatus to assess heart function, we measured various indicators of heart health, including the pressure the heart could generate and rates of heart contractions. We also examined markers of heart damage and stress, like enzymes and inflammatory signals.
Our findings were promising. The group that received MK-4 after the I/R injury showed a significant reduction in the size of heart damage, alongside improved heart function. This group also had lower levels of markers related to heart stress and damage, indicating that MK-4 might help the heart recover from the stress of a heart attack. Overall, these results suggest that vitamin K2 could be a valuable ally in enhancing heart health during recovery from ischemic events.
Read More
8
We explored the effect of dietary intake of menaquinone, commonly known as vitamin K2, on heart attack risk and overall heart health. The investigation drew on data from the Rotterdam Study, tracking 4,807 individuals who did not have prior heart attacks.
Through careful analysis, we observed a noteworthy finding: people who consumed higher amounts of menaquinone had a significantly reduced risk of coronary heart disease (CHD) and all-cause mortality. Specifically, those in the mid to upper intake levels of menaquinone exhibited a risk reduction of 27% and 57% for heart-related deaths compared to those with lower intake.
Interestingly, we found that menaquinone intake also seemed to correlate with lower instances of severe aortic calcification, suggesting its potential role in preventing vascular issues. On the other hand, our analysis indicated that phylloquinone, or vitamin K1, did not show any significant relationship with these health outcomes.
These findings underscore the importance of adequate menaquinone consumption as a potential strategy for heart attack prevention and cardiovascular health improvement.
Through careful analysis, we observed a noteworthy finding: people who consumed higher amounts of menaquinone had a significantly reduced risk of coronary heart disease (CHD) and all-cause mortality. Specifically, those in the mid to upper intake levels of menaquinone exhibited a risk reduction of 27% and 57% for heart-related deaths compared to those with lower intake.
Interestingly, we found that menaquinone intake also seemed to correlate with lower instances of severe aortic calcification, suggesting its potential role in preventing vascular issues. On the other hand, our analysis indicated that phylloquinone, or vitamin K1, did not show any significant relationship with these health outcomes.
These findings underscore the importance of adequate menaquinone consumption as a potential strategy for heart attack prevention and cardiovascular health improvement.
Read More
7
We examined the effectiveness of rivaroxaban compared to vitamin K antagonists (VKAs) in treating patients with left ventricular thrombus (LVT) following a heart attack. Our retrospective study involved 1,335 patients and found that rivaroxaban not only worked as effectively as VKAs but also led to quicker LVT resolution.
Although patients taking rivaroxaban experienced fewer adverse events, the difference in bleeding risks between the two treatments wasn't significant. These findings suggest that rivaroxaban may offer clinical advantages, but further research is necessary to confirm these results.
Although patients taking rivaroxaban experienced fewer adverse events, the difference in bleeding risks between the two treatments wasn't significant. These findings suggest that rivaroxaban may offer clinical advantages, but further research is necessary to confirm these results.
Read More
Most Useful Reviews
9
Plaque reduction
400 people found this helpful
Following a heart attack in February 2018, I adopted a plant-based diet and took this product alongside vitamin D3. Remarkably, a recent CT scan revealed that the plaque in my left artery reduced significantly from 95% to moderate, while the other arteries were clear of plaque. I'm grateful for the progress made.
Read More
9
No more nosebleeds
37 people found this helpful
I have suffered from nosebleeds since childhood. After some rhino-surgery, the surgeon said the cauterising would help. Fortunately, he was right. In winter, I still experienced them, but since taking two MK-7 capsules daily, they have completely disappeared. Additionally, knowing that vitamin K2 is beneficial for my heart and bones is a pleasant bonus.
Read More
7.5
Decalcification success
21 people found this helpful
This product has effectively removed calcium from my arteries, redirecting it to my bones and teeth. After experiencing a heart attack at 40, my resting heart rate and blood pressure were elevated. Since starting this product a few months ago, my resting heart rate has improved to the 80s, and my blood pressure readings are now normal. I take 1 capsule twice daily, and the neck pains that previously arose with exertion have significantly diminished.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.8
- All Researches
9
Coumarin indicates potential heart protection
We investigated the cardioprotective effects of a newly developed coumarin, known as 5,6-PhSHC, on heart damage caused by isoproterenol-induced myocardial infarction in rats. The study involved treating rats with 5,6-PhSHC or clopidogrel before inducing a heart attack.
Our findings showed that 5,6-PhSHC improved electrocardiogram patterns and reduced markers of heart injury. Additionally, it helped reverse tissue damage and regulated cholesterol levels. While the results are promising, more research is needed to determine its potential for human use.
Our findings showed that 5,6-PhSHC improved electrocardiogram patterns and reduced markers of heart injury. Additionally, it helped reverse tissue damage and regulated cholesterol levels. While the results are promising, more research is needed to determine its potential for human use.
Read More
9
We examined how Menaquinone-4, a form of vitamin K2, could help protect the heart during a critical event known as ischemia-reperfusion (I/R) injury, which often occurs after heart attacks. In our study, we used thirty-two rats, dividing them into three groups: a control group that experienced I/R without treatment, a group that received MK-4 before the injury, and another group that got MK-4 at the beginning of the recovery phase.
By using a specialized apparatus to assess heart function, we measured various indicators of heart health, including the pressure the heart could generate and rates of heart contractions. We also examined markers of heart damage and stress, like enzymes and inflammatory signals.
Our findings were promising. The group that received MK-4 after the I/R injury showed a significant reduction in the size of heart damage, alongside improved heart function. This group also had lower levels of markers related to heart stress and damage, indicating that MK-4 might help the heart recover from the stress of a heart attack. Overall, these results suggest that vitamin K2 could be a valuable ally in enhancing heart health during recovery from ischemic events.
By using a specialized apparatus to assess heart function, we measured various indicators of heart health, including the pressure the heart could generate and rates of heart contractions. We also examined markers of heart damage and stress, like enzymes and inflammatory signals.
Our findings were promising. The group that received MK-4 after the I/R injury showed a significant reduction in the size of heart damage, alongside improved heart function. This group also had lower levels of markers related to heart stress and damage, indicating that MK-4 might help the heart recover from the stress of a heart attack. Overall, these results suggest that vitamin K2 could be a valuable ally in enhancing heart health during recovery from ischemic events.
Read More
8
Comparative effectiveness of antithrombotic therapies
We evaluated the outcomes of patients with left ventricular thrombus (LVT) after a heart attack, focusing on dual antithrombotic therapy (DAT) versus triple antithrombotic therapy (TAT).
Analyzing a decade's worth of records from our hospital, we found that those on DAT had significantly fewer major complications after one year compared to those on TAT, particularly in terms of bleeding.
With over two-thirds of complications occurring shortly after discharge, the findings suggest that DAT may be the safer option for these patients. However, a randomized study is needed for confirmation.
Analyzing a decade's worth of records from our hospital, we found that those on DAT had significantly fewer major complications after one year compared to those on TAT, particularly in terms of bleeding.
With over two-thirds of complications occurring shortly after discharge, the findings suggest that DAT may be the safer option for these patients. However, a randomized study is needed for confirmation.
Read More
8
We examined whether novel oral anticoagulants (NOACs) are more effective than vitamin K antagonists (VKAs) for treating left ventricular thrombus in heart attack patients. In our observational study of 2328 patients, we found that 4.3% had left ventricular thrombus.
Those treated with NOACs showed faster and better thrombus resolution at one year compared to the VKA group. Additionally, major bleeding events were significantly lower in the NOAC group. These findings suggest that NOACs could offer a safer and more effective option for patients post-heart attack.
Those treated with NOACs showed faster and better thrombus resolution at one year compared to the VKA group. Additionally, major bleeding events were significantly lower in the NOAC group. These findings suggest that NOACs could offer a safer and more effective option for patients post-heart attack.
Read More
8
We explored the effect of dietary intake of menaquinone, commonly known as vitamin K2, on heart attack risk and overall heart health. The investigation drew on data from the Rotterdam Study, tracking 4,807 individuals who did not have prior heart attacks.
Through careful analysis, we observed a noteworthy finding: people who consumed higher amounts of menaquinone had a significantly reduced risk of coronary heart disease (CHD) and all-cause mortality. Specifically, those in the mid to upper intake levels of menaquinone exhibited a risk reduction of 27% and 57% for heart-related deaths compared to those with lower intake.
Interestingly, we found that menaquinone intake also seemed to correlate with lower instances of severe aortic calcification, suggesting its potential role in preventing vascular issues. On the other hand, our analysis indicated that phylloquinone, or vitamin K1, did not show any significant relationship with these health outcomes.
These findings underscore the importance of adequate menaquinone consumption as a potential strategy for heart attack prevention and cardiovascular health improvement.
Through careful analysis, we observed a noteworthy finding: people who consumed higher amounts of menaquinone had a significantly reduced risk of coronary heart disease (CHD) and all-cause mortality. Specifically, those in the mid to upper intake levels of menaquinone exhibited a risk reduction of 27% and 57% for heart-related deaths compared to those with lower intake.
Interestingly, we found that menaquinone intake also seemed to correlate with lower instances of severe aortic calcification, suggesting its potential role in preventing vascular issues. On the other hand, our analysis indicated that phylloquinone, or vitamin K1, did not show any significant relationship with these health outcomes.
These findings underscore the importance of adequate menaquinone consumption as a potential strategy for heart attack prevention and cardiovascular health improvement.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 27 Reviews
7.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Plaque reduction
400 people found this helpful
Following a heart attack in February 2018, I adopted a plant-based diet and took this product alongside vitamin D3. Remarkably, a recent CT scan revealed that the plaque in my left artery reduced significantly from 95% to moderate, while the other arteries were clear of plaque. I'm grateful for the progress made.
Read More
9
No more nosebleeds
37 people found this helpful
I have suffered from nosebleeds since childhood. After some rhino-surgery, the surgeon said the cauterising would help. Fortunately, he was right. In winter, I still experienced them, but since taking two MK-7 capsules daily, they have completely disappeared. Additionally, knowing that vitamin K2 is beneficial for my heart and bones is a pleasant bonus.
Read More
7.5
Decalcification success
21 people found this helpful
This product has effectively removed calcium from my arteries, redirecting it to my bones and teeth. After experiencing a heart attack at 40, my resting heart rate and blood pressure were elevated. Since starting this product a few months ago, my resting heart rate has improved to the 80s, and my blood pressure readings are now normal. I take 1 capsule twice daily, and the neck pains that previously arose with exertion have significantly diminished.
Read More
9
Calcium regulated
7 people found this helpful
Vitamin K2 ensures calcium is fixed in bones, preventing harmful deposits in arteries and organs, which reduces the risk of heart attack. It's an anti-aging vitamin as it combats calcification associated with ageing. K2 also supports heart health and prevents cataracts while boosting mitochondrial function and overall vitality.
Read More
9
Stronger bones
5 people found this helpful
Vitamin K2 MK7 is crucial for heart health as it directs calcium to the bones, essential for strong teeth and bones. A deficiency may lead to calcium accumulating in tissues, risking heart attack. Supplementing with K2 MK7 is vital for maintaining overall health and preventing diseases related to ageing.
Read More
Frequently Asked Questions
6
Heart health improvements
I've experienced less heart palpitations and improved energy levels since starting this supplement. It has positively impacted my heart health after my heart attack.
9
Plaque reduction
1 people found this helpful
After my heart attack, I adopted a plant-based diet and took four MK-7 pills daily. A recent calcium scoring CT scan showed a significant reduction in plaque in my artery, which is promising.
7.5
Strong bones support
Taking vitamin K2 with D3 has helped me build strong bones, directing calcium to the right places like bones and teeth, while removing it from where it shouldn't be. It plays a vital role in protecting the heart, brain, and even in cancer protection while balancing blood sugar. This combination is excellent for energy and renal health, and reduces the risk of heart attack.
9
No more nosebleeds
37 people found this helpful
I have suffered from nosebleeds since childhood. After some rhino-surgery, the surgeon said the cauterising would help. Fortunately, he was right. In winter, I still experienced them, but since taking two MK-7 capsules daily, they have completely disappeared. Additionally, knowing that vitamin K2 is beneficial for my heart and bones is a pleasant bonus.
9
Nosebleed relief
1 people found this helpful
MK-7 completely stopped my nosebleeds, which I have suffered from since childhood. I take two daily and feel satisfied, and its additional heart and bone health benefits are a fantastic bonus!
7.5
Improved bone health
18 people found this helpful
If you are supplementing with D3, make sure to include K2. D3 enhances calcium availability, and K2 transports it into bones, preventing potential heart attack risks from excess calcium in soft tissues. Since starting K2, my bone pain has decreased, my teeth are cleaner, and my skin has improved. I will continue this as it’s scarce in my diet.
9
Calcium stabilised
5 people found this helpful
I take calcium, vitamin D, and vitamin K2 daily. This combination has significantly improved my health. Vitamin K2 stabilises calcium in bones, preventing it from accumulating in the heart and other tissues, thus reducing the risk of heart attack. I trust the Now Foods brand and am delighted with the results.
7.5
Reduced mortality risk
4 people found this helpful
Taking 300 μg of vitamin K2 (MK-7) has been shown to reduce overall mortality, especially from heart attack. I combine it with vitamin D, which enhances the benefits, as they complement each other in promoting health.
0
Consult doctor advised
8 people found this helpful
I tend to experience heart palpitations, and upon discovering that MK-7 has caused this for many, I opted against using it. NOW Foods produces excellent supplements, but ensure they suit your needs. It's crucial to consult your doctor, as there remain many unknowns about supplements, so avoid overindulgence.
0
Palpitations concern
3 people found this helpful
After taking this twice, I began experiencing palpitations, leading me to suspect that K2 might be the culprit following my heart attack. I no longer continue with it.
8
We explored the effect of dietary intake of menaquinone, commonly known as vitamin K2, on heart attack risk and overall heart health. The investigation drew on data from the Rotterdam Study, tracking 4,807 individuals who did not have prior heart attacks.
Through careful analysis, we observed a noteworthy finding: people who consumed higher amounts of menaquinone had a significantly reduced risk of coronary heart disease (CHD) and all-cause mortality. Specifically, those in the mid to upper intake levels of menaquinone exhibited a risk reduction of 27% and 57% for heart-related deaths compared to those with lower intake.
Interestingly, we found that menaquinone intake also seemed to correlate with lower instances of severe aortic calcification, suggesting its potential role in preventing vascular issues. On the other hand, our analysis indicated that phylloquinone, or vitamin K1, did not show any significant relationship with these health outcomes.
These findings underscore the importance of adequate menaquinone consumption as a potential strategy for heart attack prevention and cardiovascular health improvement.
Through careful analysis, we observed a noteworthy finding: people who consumed higher amounts of menaquinone had a significantly reduced risk of coronary heart disease (CHD) and all-cause mortality. Specifically, those in the mid to upper intake levels of menaquinone exhibited a risk reduction of 27% and 57% for heart-related deaths compared to those with lower intake.
Interestingly, we found that menaquinone intake also seemed to correlate with lower instances of severe aortic calcification, suggesting its potential role in preventing vascular issues. On the other hand, our analysis indicated that phylloquinone, or vitamin K1, did not show any significant relationship with these health outcomes.
These findings underscore the importance of adequate menaquinone consumption as a potential strategy for heart attack prevention and cardiovascular health improvement.
9
We examined how Menaquinone-4, a form of vitamin K2, could help protect the heart during a critical event known as ischemia-reperfusion (I/R) injury, which often occurs after heart attacks. In our study, we used thirty-two rats, dividing them into three groups: a control group that experienced I/R without treatment, a group that received MK-4 before the injury, and another group that got MK-4 at the beginning of the recovery phase.
By using a specialized apparatus to assess heart function, we measured various indicators of heart health, including the pressure the heart could generate and rates of heart contractions. We also examined markers of heart damage and stress, like enzymes and inflammatory signals.
Our findings were promising. The group that received MK-4 after the I/R injury showed a significant reduction in the size of heart damage, alongside improved heart function. This group also had lower levels of markers related to heart stress and damage, indicating that MK-4 might help the heart recover from the stress of a heart attack. Overall, these results suggest that vitamin K2 could be a valuable ally in enhancing heart health during recovery from ischemic events.
By using a specialized apparatus to assess heart function, we measured various indicators of heart health, including the pressure the heart could generate and rates of heart contractions. We also examined markers of heart damage and stress, like enzymes and inflammatory signals.
Our findings were promising. The group that received MK-4 after the I/R injury showed a significant reduction in the size of heart damage, alongside improved heart function. This group also had lower levels of markers related to heart stress and damage, indicating that MK-4 might help the heart recover from the stress of a heart attack. Overall, these results suggest that vitamin K2 could be a valuable ally in enhancing heart health during recovery from ischemic events.
8
We examined whether novel oral anticoagulants (NOACs) are more effective than vitamin K antagonists (VKAs) for treating left ventricular thrombus in heart attack patients. In our observational study of 2328 patients, we found that 4.3% had left ventricular thrombus.
Those treated with NOACs showed faster and better thrombus resolution at one year compared to the VKA group. Additionally, major bleeding events were significantly lower in the NOAC group. These findings suggest that NOACs could offer a safer and more effective option for patients post-heart attack.
Those treated with NOACs showed faster and better thrombus resolution at one year compared to the VKA group. Additionally, major bleeding events were significantly lower in the NOAC group. These findings suggest that NOACs could offer a safer and more effective option for patients post-heart attack.
References
- Ghazouani L, Khdhiri E, Elmufti A, Zarei A, Feriani A, et al. A novel synthetised sulphonylhydrazone coumarin (E)-4-methyl-N'-(1-(3-oxo-3H-benzo[f]chromen-2- yl)ethylidene)benzenesulphonohydrazide protect against isoproterenol-induced myocardial infarction in rats by attenuating oxidative damage, biological changes and electrocardiogram. Clin Exp Pharmacol Physiol. 2022;49:1010. doi:10.1111/1440-1681.13690
- Park J, Jung JH, Choi EK, Lee SW, Kwon S, et al. Comparison of early clinical outcomes between dual antiplatelet therapy and triple antithrombotic therapy in patients with atrial fibrillation undergoing percutaneous coronary intervention. PLoS One. 2022;17:e0264538. doi:10.1371/journal.pone.0264538
- De Luca L, Putini RL, Natale E, Terranova A, Piazza V, et al. One-year clinical outcome of patients with left ventricular thrombus after acute myocardial infarction discharged on triple or dual antithrombotic therapy. J Thromb Thrombolysis. 2022;53:410. doi:10.1007/s11239-021-02577-2
- Zhang Z, Si D, Zhang Q, Qu M, Yu M, et al. Rivaroxaban versus Vitamin K Antagonists (warfarin) based on the triple therapy for left ventricular thrombus after ST-Elevation myocardial infarction. Heart Vessels. 2022;37:374. doi:10.1007/s00380-021-01921-z
- Alcalai R, Butnaru A, Moravsky G, Yagel O, Rashad R, et al. Apixaban vs. warfarin in patients with left ventricular thrombus: a prospective multicentre randomized clinical trial‡. Eur Heart J Cardiovasc Pharmacother. 2022;8:660. doi:10.1093/ehjcvp/pvab057
- Wang MT, Hung CC, Lin KC, Mar GY, Kuo SH, et al. Comparison of effects of triple antithrombotic therapy and dual antiplatelet therapy on long-term outcomes of acute myocardial infarction. Heart Vessels. 2021;36:345. doi:10.1007/s00380-020-01708-8
- Jones DA, Wright P, Alizadeh MA, Fhadil S, Rathod KS, et al. The use of novel oral anticoagulants compared to vitamin K antagonists (warfarin) in patients with left ventricular thrombus after acute myocardial infarction. Eur Heart J Cardiovasc Pharmacother. 2021;7:398. doi:10.1093/ehjcvp/pvaa096
- Hassan AE, Hadhoud S, Elmahdi E, Elkattawy HA. Potential Cardioprotective Role of Menaquinone-4 Against Cardiac Ischemia-reperfusion Injury. J Cardiovasc Pharmacol. 2023;81:381. doi:10.1097/FJC.0000000000001413
- Geleijnse JM, Vermeer C, Grobbee DE, Schurgers LJ, Knapen MH, et al. Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: the Rotterdam Study. J Nutr. 2004;134:3100.
